Viral Studies in Burkitt Lymphoma
نویسندگان
چکیده
منابع مشابه
Cytogenetic studies in non-African Burkitt lymphoma.
A particular translocation between chromosomes 8 and 14 has been found repeatedly in cytogenetic studies of Burkitt lymphoma, both of African and non-African origin. We report here our findings in cytogenetic studies of direct tumor preparations from 18 non-African Burkitt lymphoma patients, 9 of whom also had cell lines available for study. A t(8;14) was found in direct tumor material in 10 of...
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PURPOSE Some EBV-directed therapies are predicted to be effective only when lytic viral replication occurs. We studied whether cyclophosphamide chemotherapy induces EBV to switch from latent to lytic phases of infection in a series of EBV-associated Burkitt lymphomas. EXPERIMENTAL DESIGN Children with first presentation of an expanding, solid maxillary or mandibular mass consistent with Burki...
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Burkitt lymphoma (BL) is a highly aggressive non-Hodgkin lymphoma, composed of a monomorphic population of medium-sized B cells with a high proliferation rate and a consistent MYC translocation. Epstein-Barr virus (EBV) has been associated with BL with different frequencies depending on the clinical variant. Kaposi sarcoma-associated herpesvirus, or human herpesvirus 8 (HHV-8), infects a wide r...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2008
ISSN: 0002-9173,1943-7722
DOI: 10.1309/2cnawy6gar0vqaxx